PT-141
Sexual Health & Wellness

PT-141

The arousal peptide—ideal for men and women.

PT-141Subcutaneous injectionMenWomenOff-label use
Starting at$189$189.00 for a 1 month supply.
Select treatment

Subcutaneous injection

Select duration
PT-141 (1 Month)$189
About

What is PT141?

PT-141 (Bremelanotide) is a centrally acting melanocortin receptor agonist used to enhance sexual desire and arousal in women. Originally developed to treat sexual dysfunction, it is FDA-approved for hypoactive sexual desire disorder (HSDD) in premenopausal women. Unlike traditional ED medications, PT-141 works through the brain rather than blood flow.

Snapshot

The essentials

Onset
45–60 min
Administered via subcutaneous injection before sexual activity.
Mechanism
CNS-based
Acts on melanocortin receptors, independent of blood flow.
Physician reviewed
US-licensed
Off-label use reviewed by your clinician.
Best for
Low desire
Arousal-related concerns for men and women.
How it works

Your protocol, step by step

1

CNS-Based Arousal Enhancement

PT-141 activates melanocortin receptors (MC3R and MC4R) in the hypothalamus, increasing sexual desire and drive by acting on the central nervous system.

2

Independent of Blood Flow

Unlike PDE5 inhibitors (like sildenafil or tadalafil), PT-141 does not depend on nitric oxide pathways or vascular mechanisms—making it effective for both genders and for arousal-related dysfunction.

3

Rapid, On-Demand Effect

Administered via subcutaneous injection 45–60 minutes before sexual activity, PT-141 enhances arousal, responsiveness, and sensitivity for several hours.

Benefits

What patients look for

Acts on melanocortin receptors in the central nervous system
Studied for low sexual desire and arousal-related concerns
May be considered when PDE5 inhibitors are not appropriate
Bremelanotide (the active ingredient) is FDA-approved as Vyleesi® for hypoactive sexual desire disorder (HSDD) in premenopausal women. Use in men is off-label.
Non-hormonal; risks, benefits, and alternatives reviewed by your clinician
FAQ

Questions, answered

PT-141 stimulates the brain's arousal centers through the melanocortin system.
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