Low Dose Naltrexone
LOW DOSE NALTREXONE

Low Dose Naltrexone

Immune Balance. Natural Resilience.

Immune & RecoveryNaltrexone — compounded oral, low doseMenCompounded
Starting at$99$99.00 for a 1 month supply
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Oral tablet · nightly

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Low Dose Naltrexone (1 Month Supply)$99
About

A low dose. A different medicine.

Naltrexone was originally FDA-approved at 50 mg to block opioid receptors in addiction medicine. Compounded at just 1.5–4.5 mg—roughly one-tenth the standard dose—it behaves like a completely different drug. At these microdoses, LDN briefly touches opioid receptors at night, then lets go. The body responds by producing more of its own endorphins, enkephalins, and regulatory signals—recalibrating the immune system and quieting low-grade inflammation rather than suppressing it.

Snapshot

The essentials

Daily dose
1.5–4.5 mg
Compounded microdose, taken orally at night.
Evidence
300+ studies
Studied for autoimmune disease, chronic pain, and neuroinflammation.
Profile
Non-opioid
Non-addictive at low doses with a strong safety profile.
Time to results
Weeks 4–8
Improved energy, mood stabilization, and reduced inflammatory symptoms.
How it works

Your protocol, step by step

1

ENDORPHIN REBOUND

Low Dose Naltrexone (LDN) transiently blocks opioid receptors for a few hours. When the blockade wears off, the body overcompensates by producing more endorphins and enkephalins—natural mood-regulating and immune-supporting peptides.

2

IMMUNE MODULATION

LDN modulates microglial activity in the brain and peripheral immune cells, reducing pro-inflammatory cytokines. This makes it beneficial for autoimmune conditions, chronic pain, and neuroinflammation.

3

GLIAL CELL REGULATION

By calming overactivated microglial cells, LDN may reduce neuroinflammation and support healthier brain function—with emerging evidence for benefits in fatigue, mood, and cognitive clarity.

Benefits

What patients look for

Supports healthy immune system regulation
May reduce chronic pain and inflammation
Promotes natural endorphin and enkephalin production
Emerging evidence for autoimmune and neurological support
Well-tolerated at low doses with a strong safety profile
What's included

Included in your plan

Same molecule. New mechanism.
Studied for autoimmune disease
Studied for chronic pain
Studied for neuroinflammation
FAQ

Questions, answered

LDN is taken orally, typically at night to align with the body's natural endorphin rhythm. Most patients start at the lowest dose and gradually titrate up. Week 1–2: Possible vivid dreams as the body adjusts; some notice early energy improvements. Weeks 4–8: Improved energy, mood stabilization, and reduced inflammatory symptoms. 3+ months: Cumulative immune-modulating and anti-inflammatory benefits. Best results combined with anti-inflammatory nutrition, regular movement, and stress management.
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Built for the body that's running hot. Most men don't have a single diagnosis—they have a stack. Persistent fatigue. Joint stiffness that lingers. Sleep that doesn't restore. Recovery that takes longer than it used to. LDN is for the quiet, chronic background noise that standard panels miss.

Prescription products require a medical evaluation by a licensed provider. Treatment is only prescribed when clinically appropriate. Compounded medications are not FDA-approved products. Prices are as listed and may vary by dose, supply length and pharmacy.