Bupropion / Zyban
Quit without nicotine.
About Bupropion
Bupropion is an atypical antidepressant that is FDA-approved for smoking cessation under the brand name Zyban. It works by altering levels of dopamine and norepinephrine in the brain — chemicals involved in addiction and mood regulation. Unlike nicotine replacement therapy, Bupropion is a non-nicotine oral medication that reduces cravings, helps manage withdrawal symptoms, and improves quit success rates.
The essentials
Your protocol, step by step
DOPAMINE & NOREPINEPHRINE MODULATION
Bupropion inhibits the reuptake of dopamine and norepinephrine, helping stabilise mood and reduce irritability and cravings commonly experienced during nicotine withdrawal.
CRAVING REDUCTION
By altering brain reward circuits tied to nicotine, Bupropion decreases the pleasure derived from smoking, helping break the behavioural and chemical cycle of addiction.
NICOTINE-FREE THERAPY
As a non-nicotine option, Bupropion helps smokers quit without perpetuating physical nicotine dependence.
What patients look for
Questions, answered
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